Due 11/10: Central Dogma Assignment

Please submit your responses to LesleyBioHomework@gmail.com by 5pm next Monday, 11/10.

1. The genetic code is described as being universal. Describe what this means.

2. Is there only one codon for each amino acid in the generic code? Explain why or why not.

3. What is it about the genetic code that allows some substitution mutations to be silent?

4. Nucleotide bases of mRNA are read by the ribosome in groups of

(a) 2 (b) 3 (c) 4 (d) 5

which are called

(a) codons (b) anticodons (c) base pairs (d) reading frames

5. When does the ribosome stop making a protein from an mRNA?
(a) Once it reaches the very end of the mRNA strand
(b) Once it reaches a stop codon
(c) Once it hits a secondary mRNA structure that obstructs its progress
(d) Once it reads three alanine codons in a row

6. Match each process to the polymer it produces

____ Replication (a) Protein
____ Transcription (b) mRNA
____ Translation (c) DNA

7. Define each term clearly in one or two sentences

Gene
Chromosome
Genome

8. A nonfunctional chromalin protein has all the same amino acids as a normal, properly functioning chromalin protein except it has a leucine where there is normally a proline. What kind of mutation is responsible for this change?

(a) insertion (b) deletion (c) substitution (d) frameshift

9. A nonfunctional nurilase enzyme in an abnormal individual is missing the last 10 amino acids as a compared to a properly functioning nurilase enzyme in a normal individual. What kind of mutation is responsible for this change?

(a) nonsense (b) missense (c) silent (d) amplification

10. What is the sequence of bases for an mRNA transcribed from the template-strand DNA sequence GGCAAGTTCAGCC?

11. What is the amino acid sequence that the DNA template strand sequence CATACCCTAGGCGA codes for?

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